Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp104 | Calciotropic and phosphotropic hormones and mineral metabolism | ECTS2013

Neonatal neuroendocrine alterations impair tooth eruption, enamel mineralization, and leptin and corticosterone secretion in adulthood

de Mello Wagner Garcez , de Morais Samuel Rodrigues Lourenco , Delbem Alberto Carlos Botazzo , Dornelles Rita Cassia Menegati , Antunes-Rodrigues Jose , de Castro Joao Cesar Bedran

There is a growing body of evidence indicating the important role of the neonatal steroid milieu in programming sexually dimorphic pattern in various physiological systems. We tested the hypothesis that abnormal exposure to steroid hormones within a critical developmental period elicits permanent changes on tooth eruption, enamel mineralization, and leptin and corticosterone concentrations in adulthood. Newborn Wistar rats were divided into four groups, two male groups and two...